Tadalista 60 mg are primarily used for the treatment of erectile dysfunction (ED) in men. Erectile dysfunction is a common condition characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Tadalafil, the active ingredient in these tablets, belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors.
When a man is sexually stimulated, the release of nitric oxide in the erectile tissue of the penis leads to the production of cyclic guanosine monophosphate (cGMP). This chemical messenger relaxes the smooth muscles in the blood vessels of the penis, allowing them to dilate and increase blood flow, which results in an erection.
In individuals with erectile dysfunction, there is an overproduction of an enzyme called phosphodiesterase type 5 (PDE5), which breaks down cGMP, leading to a decrease in blood flow to the penis and difficulty achieving or maintaining an erection. Tadalafil inhibits the action of PDE5, allowing cGMP to accumulate and promoting increased blood flow to the penis, thereby improving erectile function.
Tadalafil 60 mg tablets are typically taken orally, as needed, prior to anticipated sexual activity. The onset of action usually occurs within 30 minutes to 1 hour after ingestion, and the effects may last for up to 36 hours, earning tadalafil the nickname "the weekend pill." This prolonged duration of action allows for greater spontaneity in sexual activity compared to other medications used to treat ED.
